USE OF SULPHATED GLYCOLIPIDS AS PROMOTERS OF NEURITIC GROWTH, MYELINATION AND INHIBITING THE PROLIFERATION OF ASTROGLIA AND MICROGLIA
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United States of America Patent
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Issued Date -
Oct 29, 2015
app pub date -
Jul 2, 2013
filing date -
Jul 4, 2012
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Abandoned
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Abstract
A compound having formula I, in which R1 is an alkenyl group C5-C25 containing one or more double carbon-carbon bonds, R2 is selected independently from the group consisting of methyl and fluorinated methyl, and R3 and/or R4 is a SO3M group, in which M is selected from the group consisting of hydrogen, alkali metal, ammonium and quaternary amine, the other being hydrogen or acyl is provided. The compound can be used for the production of a drug for the treatment of central nervous system disorders selected from the group consisting of lesions caused by CNS trauma, demyelinating diseases, neuro-inflammatory diseases and mental disorders caused a low level of BDNF.
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