HYDROGELATORS COMPRISING D-AMINO ACIDS

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United States of America Patent

APP PUB NO 20150306232A1
SERIAL NO

14441773

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Abstract

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Described herein are compounds comprising an oligopeptide and a non-steroidal antiinflammatory agent. The compounds self-assemble into supramolecular hydrogels and can be used as topical treatments for inflammatory conditions, such as osteoarthritis. Also described herein are oligopeptides compounds made from D-amino acid residues that form supramolecular hydrogels. The compounds may be functionalized with active agents, such as anticancer therapeutic agents, antiinflammatory agents, or imaging agents, therefore providing new mechanisms for delivery of active agents.

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Patent Owner(s)

Patent OwnerAddress
BRANDEIS UNIVERSITY415 MAIN STREET MS 009 WALTHAM MA 02453-2728

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
LI, Jiayang Waltham, US 10 14
XU, Bing Newton, US 129 999
YI, Kuang Waltham, US 3 6

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