METHOD FOR REPROGRAMMING OF HUMAN DENTAL PULP CELL USING OCT4 AND SOX2 AND USE THEREOF

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United States of America Patent

APP PUB NO 20150299665A1
SERIAL NO

14340991

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Abstract

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The present invention relates to a method for producing endothelial progenitor cells, comprising a method for producing induced pluripotent stem cells by using only Oct4 and Sox2 as a reprogramming factor of human dental pulp cells, and differentiating endothelial progenitor cells from the induced pluripotent stem cells produced by the method for producing induced pluripotent stem cells. Moreover, the present invention relates to a method for producing endothelial cells, comprising differentiating endothelial cells from endothelial progenitor cells produced by the method for producing the endothelial progenitor cells. Additionally, the present invention relates to a method for producing smooth muscle cells, comprising differentiating smooth muscle cells from endothelial progenitor cells produced by the method for producing the endothelial progenitor cells.

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Patent OwnerAddress
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY125 GWAHAK-RO YUSEONG-GU DAEJEON 34141 34141

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cho, Yee Sook Daejeon, KR 17 23
Na, Hee Jun Daejeon, KR 1 0
Yoo, Chae Wha Daejeon, KR 1 0

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