BICYCLIC PYRAZOLONE COMPOUNDS AND METHODS OF USE
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United States of America Patent
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Issued Date -
Oct 22, 2015
app pub date -
Apr 16, 2015
filing date -
Apr 22, 2014
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Abandoned
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Abstract
The present invention provides substituted bicyclic pyrazolone compounds, which are used to inhibit or modulate the activity of receptor tyrosine kinases, especially Axl, Mer, c-Met and Ron. The invention also provides pharmaceutical compositions comprising the compound disclosed herein, and a method of preventing, treating or lessening the severity of a proliferative disorder in a patient with the compounds or the pharmaceutical compositions disclosed herein.
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