Radiofluorination method
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United States of America Patent
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Jan 2, 2018
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app pub date -
Jul 30, 2013
filing date -
Jul 30, 2012
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Abstract
A method of conducting radiofluorination of a substrate, includes: (a) contacting an aqueous solution of [18F] fluoride with a polymer supported phosphazene base for sufficient time for trapping of [18F] fluoride on the polymer supported phosphazene base; and (b) contacting a solution of the substrate with the polymer supported phosphazene base having [18F] fluoride trapped thereon obtained in step (a) for sufficient time for a radiofluorination reaction to take place.
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