Sequencing Performance With Additives
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United States of America Patent
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Issued Date -
Oct 8, 2015
app pub date -
Apr 6, 2015
filing date -
Apr 7, 2014
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Abstract
Methods are described which utilize additives that ease secondary structure of DNA to improve sequencing performance. In one embodiment, said additive is betaine. The addition of betaine leads to decreased error rates.
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