Compositions and Methods for Molecular Inversion Probe Assays
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United States of America Patent
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Oct 8, 2015
app pub date -
Apr 3, 2015
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Apr 4, 2014
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Abstract
The invention provides methods and compositions to enhance the efficiency and sensitivity of molecular inversion probe (MIP) reactions. Probes include elements that allow MIP ends to abut for ligation while avoiding the possibility of polymerase strand displacement errors. Elements facilitate multiplexed detections, including MIP reaction product detections employing next generation sequencing (NGS) techniques.
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