COMPOSITIONS AND METHODS FOR TREATING PROTEINOPATHIES
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United States of America Patent
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Issued Date -
Oct 8, 2015
app pub date -
Nov 4, 2013
filing date -
Nov 5, 2012
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Abstract
This disclosure relates to methods for improving neural function in a mammal with a proteinopathy comprising administering a therapeutically effective amount of an agent that increases glucocerebrosidase activity in the mammal. Also disclosed are methods for reducing toxic lipids, reducing α-synuclein, and/or inhibiting the accumulation of protein aggregates in a mammal with a proteinopathy comprising administering a therapeutically effective amount of an agent that increases glucocerebrosidase activity.
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