BIOMARKER FOR USE IN TREATING ANEMIA
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United States of America Patent
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Issued Date -
Oct 1, 2015
app pub date -
Oct 23, 2013
filing date -
Oct 24, 2012
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Abstract
Provided herein are methods of treating diseases associated with anemia or ineffective erythropoiesis by using the level and/or activity of a ligand of an activin receptor, in particular, Growth differentiation factor 11 (GDF11), as an indicator of responsiveness of a patient to the treatment, efficacy of the treatment, or appropriate dosage for the treatment with an activin type II receptor inhibitor.
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