Method for Preparation of a High Concentration Liquid Formulation of an Antibody

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United States of America Patent

APP PUB NO 20150266965A1
SERIAL NO

14437902

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Abstract

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The present invention provides a method for preparation of a high concentration liquid formulation (HCLF) of an antibody or a fragment thereof. The present invention also relates to a method for stabilizing an anti-CD20 antibody or a fragment thereof in a liquid pharmaceutical formulation. Furthermore, the present invention relates to a liquid pharmaceutical formulation of a veltuzumab antibody or a fragment thereof comprising at least 155 mg/mL of a veltuzumab antibody or a fragment thereof.

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Patent Owner(s)

Patent OwnerAddress
TAKEDA PHARMACEUTICAL COMPANY LIMITED1-1 DOSHOMACHI 4-CHOME CHUO-KU OSAKA-SHI OSAKA 541-0045

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Becker, Gerhard Allensbach, DE 21 108
Ise, Wolfgang Konstanz, DE 6 3
Rast, Markus Radofzell, DE 7 19
Skufca, Peter Stockach, DE 11 20
Steinhilber, Wolfram Stockach, DE 10 6
Volz, Jürgen Radolfzell, DE 7 6

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