INHIBITION OF INTERLEUKIN-8 AND/OR ITS RECEPTOR CXCR1 IN THE TREATMENT OF HER2/HER3-OVEREXPRESSING BREAST CANCER

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United States of America Patent

APP PUB NO 20150266961A1
SERIAL NO

14387602

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Abstract

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The present invention relates to a method for treating breast cancer in a subject having a breast cancer characterized by activation of the HER2/HER3 heterodimer, which method comprises the step of administering to said subject a therapeutically effective amount of a modulator of interleukin 8 (IL8) and/or of its receptor chemokine (C-X-C motif) receptor 1 (CXCR1).

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS FORSCHUNGSSTIFTUNG ZWEIGNIEDERLASSUNG FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH4058 BASEL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aceto, Nicola Casale Monferrato, IT 10 15
Bentires-Alj, Mohamed Kembs-Loechle, FR 9 10

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