GOLD(I) COMPLEXES WITH T-BUTYL PHOSPHINE AND DIALKYL DITHIOCARBAMATE LIGANDS

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United States of America Patent

APP PUB NO 20150266909A1
SERIAL NO

14219794

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Gold(I) complexes of formulae [Au{P(t-Bu)3}(S2CN(CH3)2)] (1), and [Au{P(t-Bu)3}(S2CN(C2H5)2)] (2) have been prepared by the reaction of equimolar amounts of [Au{P(t-Bu)3}(Cl)] with sodium dimethyldithiocarbamate monohydrate, and sodium diethyldithiocarbamate trihydrate respectively. Both complexes (1) and (2) are iso-structural having linear geometry. These gold(I) dithiocarbamate complexes show in vitro cytotoxic activities against A549 (human lung carcinoma), HeLa (human cervical cancer) and MCF7 (human breast cancer) cell lines.

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Patent Owner(s)

Patent OwnerAddress
KING FAHD UNIVERSITY OF PETROLEUM AND MINERALSP O BOX 5071 INNOVATION AND INDUSTRIAL RELATION INNOVATION CLUSTER BUILDING DTV DHAHRAN 31261
KING ABDULAZIZ CITY FOR SCIENCE AND TECHNOLOGY11442 RIYADH

International Classification(s)

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  • 2014 Application Filing Year
  • C07F Class
  • 1196 Applications Filed
  • 979 Patents Issued To-Date
  • 81.86 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20142015201620172018201920202021202220230255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Altaf, Muhammad Dhahran, SA 44 54
Isab, Anvarhusein Abdulkadir Dhahran, SA 23 35
Monim-ul-Mehboob, Muhammad Dhahran, SA 7 5
Seliman, Adam Ahmed Abdallah Dhahran, SA 6 4
Wazeer, Mohammed Ismail Dhahran, SA 3 4

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  • 4 Citation Count
  • C07F Class
  • 32.55 % this patent is cited more than
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges1943403812632101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 70020406080100120140160180200220240260280300320340360

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