METHOD OF PREDICTING A PREDISPOSITION TO QT PROLONGATION
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United States of America Patent
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Sep 17, 2015
app pub date -
May 28, 2015
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Mar 29, 2007
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Abstract
The present invention describes an association between genetic polymorphisms in the ceramide kinase-like (CERKL) gene and a predisposition to prolongation of the QT interval, and provides related methods for the prediction of such a predisposition, the administration of QT interval-prolonging compounds to individuals having such a predisposition, and determining whether a compound is capable of inducing QT prolongation.
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