NANOMATERIAL-INDUCED CYTOTOXICITY DETECTION COMPOSITION AND KIT, AND NANOMATERIAL-INDUCED CYTOTOXICITY DETECTION METHOD

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United States of America Patent

APP PUB NO 20150253328A1
SERIAL NO

14358224

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Abstract

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The present invention concerns a detection marker which is specific to nanomaterial-induced cytotoxicity, and provides: a nanomaterial-induced cytotoxicity detection composition and kit, comprising an ERK gene which is specifically overexpressed when nanomaterial-induced cytotoxicity is present, an Egr-1 gene which is activated by the ERK gene, and an agent for measuring the level of the mRNA thereof or protein thereof; and a method for detecting nanomaterial-induced cytotoxicity by using the composition and kit. The composition, the kit and the detection method according to the present invention allow straightforward and accurate detection of cytotoxicity induced by nanomaterials comprised in, for example, the cells of nanomaterials.

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Patent Owner(s)

Patent OwnerAddress
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION145 ANAM-RO SEONGBUK-GU SEOUL 02841

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jeong, Sang Hoon Seoul, KR 13 11
Son, Sang-Wook Seoul, KR 1 0

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