Method for in-vitro preparation of double-layered virus-like particles of rotavirus

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United States of America Patent

PATENT NO 9862933
SERIAL NO

14429586

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Abstract

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The invention relates to a method for preparing double-layered virus-like particles of rotavirus in vitro. The method comprises the following steps: purifying rotavirus VP6 proteins from a lysis supernatant, and in vitro assembling double-layered virus-like particles consisting of VP2 proteins and VP6 proteins, wherein the proteins and the virus-like particles can be used for preventing or reducing the clinical symptoms caused by rotavirus infection.

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Patent Owner(s)

Patent OwnerAddress
XIAMEN UNIVERSITY361000 SIMING SOUTH ROAD XIAMEN FUJIAN PROVINCE NO 422 XIAMEN CITY FUJIAN PROVINCE 361000
XIAMEN INNOVAX BIOTECH CO LTD1ST FLOOR 50 SHAN BIAN HONG EAST ROAD HAICANG DISTRICT XIAMEN FUJIAN 361022 CHINA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ge, Shengxiang Xiamen, CN 25 31
Guo, Qingshun Xiamen, CN 3 0
Li, Tingdong Xiamen, CN 8 1
Xia, Ningshao Xiamen, CN 79 170
Xu, Feihai Xiamen, CN 4 0
Zhang, Jun Xiamen, CN 1152 7034

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