NOVEL ANTIBODIES INHIBITING C-MET DIMERIZATION AND USES THEREOF
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Sep 10, 2015
app pub date -
Mar 17, 2015
filing date -
Jul 12, 2007
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The present inventions relates to a process for the selection of anti c-Met antibodies capable to inhibit both ligand-dependent and ligand-independent activation of c-Met. More particularly, said process is based on the inhibition of the c-Met dimerization. In another aspect, the present invention concerns such antibodies and compositions comprising such antibodies for the preparation of a medicament to treat cancer. Diagnosis process and kits are also part of the invention.
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