VACCINE COMPOSITIONS AND METHODS OF USE
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United States of America Patent
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Sep 10, 2015
app pub date -
Sep 23, 2013
filing date -
Sep 21, 2012
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Abstract
The present disclosure provides vaccine compositions comprising at least one adjuvant and at least one antigen, wherein the adjuvant is a cationic lipid. The disclosure also provides methods of treating a disease in a mammal, methods of preventing a disease in a mammal, and methods of effecting antigen cross presentation to induce a humoral immune response and a cellular immune response in a mammal utilizing the vaccine compositions. Cross presentation of various antigens can be achieved by formulating the specific antigens with cationic lipids possessing adjuvant properties.
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