Methods and tools for identification of RSK/MSK kinase inhibitors
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United States of America Patent
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Jan 3, 2017
Grant Date -
Sep 3, 2015
app pub date -
Sep 30, 2013
filing date -
Sep 28, 2012
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Abstract
The present invention concerns 3D-crystals of complexes of ribosomal S6 kinase (RSK) and mitogen- and stress-activated protein kinase (MSK) proteins and their ligands, as well as methods for crystallization, three-dimensional structure determination and structure assisted methods for identifying ligands of said proteins.
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