Human domain antibodies against components of the human insulin-like growth factor (IGF) system
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United States of America Patent
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May 23, 2017
Grant Date -
Sep 3, 2015
app pub date -
May 13, 2015
filing date -
Oct 7, 2009
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Abstract
Antibodies and antibody fragments that bind to insulin-like growth factor (IGF) 1 receptor (IGF-1R) or IGF-2, as well as methods of using the antibodies for inhibiting the IGF-mediated signaling pathway, inhibiting IGF-1R signaling, and treating cancer, are described. A method of detecting the presence of IGF-1R or IGF-2 in a sample using the disclosed antibodies and antibody fragments is also described.
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