Means and methods for breaking noncovalent binding interactions between molecules
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United States of America Patent
Stats
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Dec 26, 2017
Grant Date -
Sep 3, 2015
app pub date -
May 5, 2015
filing date -
Jan 25, 2005
priority date (Note) -
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status (Latency Note)
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Abstract
Described are multimeric proteinaceous molecules comprising at least two members that bind each other via a region of noncovalent interaction, wherein a first of the members comprises a conditionally reactive group that, when activated, cleaves a covalent bond within the first member. Cleavage of the covalent bond results in a reduction in the binding strength with which the at least two members bind to each other via the region of noncovalent interaction. The reduction in the binding strength can result in the separation of the members under mild conditions.
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| Country | kind | publication No. | Filing Date |
|---|---|---|---|
| EP | A1 | EP1683808 | Jan 25, 2005 |
| AU | B2 | AU2006209106 | Jan 25, 2006 |
| US | B2 | US9079941 | Jan 25, 2006 |
| CA | C | CA2595727 | Jan 25, 2006 |
| JP | B2 | JP4979593 | Jan 25, 2006 |
| EP | B1 | EP1841791 | Jan 25, 2006 |
| WO | A2 | WO2006080837 | Jan 25, 2006 |
| CN | B | CN101146824 | Jan 25, 2006 |
| IL | A | IL184766 | Jul 22, 2007 |
| KR | A | KR20070119618 | Aug 17, 2007 |
International Classification(s)
- 2015 Application Filing Year
- A61K Class
- 16157 Applications Filed
- 11882 Patents Issued To-Date
- 73.55 % Issued To-Date
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Patent Citation Ranking
- 0 Citation Count
- A61K Class
- 0 % this patent is cited more than
- 8 Age
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