Importance

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Abstract

Formula (1), X₁ represents O or NR₆, X₂ represents O or NR₆, X₃ represents O or NR₁, R₁ represents H or C₁ to C₃ alkyl, R₂ represents H, or linear or branched C₁-C₈ alkyl optionally including one or more heteroatoms, cyclopropyl, cyclobutyl, cyclohexyl or oxetanyl or amino acid side chain or protected amino acid side chain, or R₁ and R₂ may form together a saturated, partly saturated or unsaturated 5 or 6 membered ring system, optionally substituted, R₃ represents H, cyclopentyl, cyclohexyl, aryl or hydroxyaryl, aryl or hydroxyaryl being optionally substituted by fluorine, or linear or branched C₁ to C₈ alkyl optionally including a hetero atom, R₄ represents phenyl or 5- or 6-membered heterocycles including one or more nitrogen or oxygen atoms optionally substituted with 1 to 4, respectively 5 fluorine atoms, and R₆ represents H, or linear or branched alkyl chain having 1 to 3 carbon atoms.

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First Claim