Process for preparing cinacalcet and pharmaceutically acceptable salts thereof
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United States of America Patent
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Mar 22, 2016
Grant Date -
Sep 3, 2015
app pub date -
Sep 9, 2013
filing date -
Sep 7, 2012
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Abstract
The present patent application relates to a process for preparing, cinacalcet or a pharmaceutically acceptable salt thereof, which comprises reacting 3-trifluoromethylbenzaldehyde having the following formula (II) with the phosphorus-comprising derivative having the following formula (III) in which R1 and R2, which may be identical or different, are each a (C1-C6)alkyl group. The present invention also relates to the phosphorus-comprising derivative having the formula (III), to the use thereof and to the process for preparing same. The present invention also relates to the phosphate salt of cinacalcet and to uses thereof.
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