METHODS AND COMPOSITIONS FOR INHIBITING GRAM POSITIVE BACTERIA
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United States of America Patent
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Issued Date -
Sep 3, 2015
app pub date -
Aug 20, 2013
filing date -
Aug 20, 2012
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Abandoned
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Abstract
Methods and compositions are provided for treating or preventing a Gram-positive bacteria infection using an inhibitor of lipo-teichoic acid synthase (LtaS). In some embodiments, the inhibitor is a small molecule. In certain embodiments, the inhibitor is 2-oxo-2-(5-phenyl-1,3,4-oxadiazol-2-ylamino)ethyl 2-naphtho[2,1-b]furan-1 -ylacetate, or a salt thereof.
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