Solid gel amplification method and apparatus for platform molecular diagnostics
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United States of America Patent
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May 1, 2018
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Feb 25, 2013
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May 9, 2012
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Abstract
The present invention provides for a novel system and method for amplification and detection of nucleic acids within a miniaturized device wherein sample administration occurs via capillary forces through a channel created by drying a hydrogel containing all components needed for a cell-free, enzymatic, nucleic-acid amplification system other than the template nucleic acid or precursor thereto, and wherein an aqueous sample is provided to the desiccated hydrogel, and the hydrogel is rehydrated, through capillary forces.
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