METHOD FOR EVALUATING BLOOD COAGULATION REACTION

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United States of America Patent

APP PUB NO 20150240287A1
SERIAL NO

14431425

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Various methods for evaluating hemostatic effect and various blood coagulation initiation reagents were studied to construct a method for evaluating blood coagulation reaction mediated by a substance having an activity of substituting for coagulation factor VIII (FVIII). As a result, it was discovered that by using a coagulation initiation reagent containing activated coagulation factor XI (FXIa) and phospholipids, the effect of a substance having an activity of substituting for coagulation factor VIII (FVIII) on blood coagulation reaction can be evaluated using the amount of thrombin generated in the blood sample as an indicator.

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Patent Owner(s)

Patent OwnerAddress
CHUGAI SEIYAKU KABUSHIKI KAISHA5-1 UKIMA 5-CHOME KITA-KU TOKYO 115-8543

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kitazawa, Takehisa Shizuoka, JP 24 363
Shima, Midori Nara, JP 14 33
Soeda, Tetsuhiro Shizuoka, JP 34 649

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