MSF REPROGRAMS MYOFIBROBLASTS TOWARD LACTATE PRODUCTION AND FUEL ANAERBOIC TUMOR GROWTH

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United States of America Patent

APP PUB NO 20150240240A1
SERIAL NO

14427549

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Presented herein is a method for treating a subject afflicted with a tumor comprising administering to the subject a therapeutically effective amount of an agent that inhibits the MSF/Cdc42/NFkB cascade in the subject's tumor-associated fibroblasts.

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Patent Owner(s)

Patent OwnerAddress
THOMAS JEFFERSON UNIVERSITY1020 WALNUT STREET PHILADELPHIA PA 19107

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lisanti, Michael P Manchester, GB 51 52

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