BIOCHEMICAL STRESS RESISTANT MICROBIAL ORGANISM
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United States of America Patent
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Issued Date -
Aug 27, 2015
app pub date -
Oct 4, 2013
filing date -
Oct 5, 2012
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Abandoned
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Abstract
It is disclosed a non-naturally occurring microbial organism comprising at least one exogenous nucleic acid encoding an enzyme, or a portion thereof, selected from the group of ammonia lyase. Preferably, the enzyme is PAL3, and the at least one exogenous nucleic acid is obtained from Arabidopsis thaliana. The non-naturally occurring microbial organism has an increased resistance to biochemical stress compared to the starting microbial organism, as induced for instance by oxidative stress or organic acid stress. Preferably, the non-naturally occurring microbial organism is a yeast and it may be used for fermenting a carbon source obtained from a ligno-cellulosic feedstock.
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