ANTI-MCAM ANTIBODIES AND ASSOCIATED METHODS OF USE
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United States of America Patent
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Issued Date -
Aug 27, 2015
app pub date -
Sep 9, 2013
filing date -
Sep 10, 2012
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Abstract
Described herein are anti-MCAM antibodies and antigen binding fragments thereof that are capable of inhibiting the interaction between MCAM and its ligand, a protein comprising a laminin α-4 chain. These anti-MCAM antibodies and antigen binding fragments thereof may be useful for, for example, treating inflammatory conditions characterized by the infiltration of MCAM-expressing cells into a site of inflammation in the body.
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