Modulation of the Interaction Between SorLA and GDNF-Family Ligand Receptors
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United States of America Patent
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Issued Date -
Aug 27, 2015
app pub date -
Apr 8, 2015
filing date -
Jun 14, 2010
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Abandoned
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Abstract
The present invention relates to a method to increase the survival of neurons by modulating the interaction between Sor LA and GDNF-family ligand receptors. The agent used to modulate the interaction between the SorLA and GDNF-family ligand receptors are selected from proteins, peptides, antibodies or small organic compounds. The invention also relates to a pharmaceutical compositions comprising these agent as well as the use of said agent or pharmaceutical composition in the treatment of a disease associated with the loss of neurons and/or wherein the survival of neurons are desired.
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