Stable, Low Viscosity Antibody Formulation

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United States of America Patent

SERIAL NO

14437585

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Abstract

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The present invention relates to a stable, low viscosity antibody formulation, wherein the formulation comprises a high concentration of anti-IL6 antibody. In some embodiments, the invention is directed to a stable, low viscosity antibody formulation comprising about 50 mg/mL to about 400 mg/mL of an anti-IL6 antibody, and arginine, wherein the antibody formulation is in an aqueous solution and has a viscosity of less than 20 cP at 23° C. Also provided are methods of making and methods of using such antibody formulations.

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Patent Owner(s)

Patent OwnerAddress
MEDIMMUNE LIMITEDMILSTEIN BUILDING GRANTA PARK CAMBRIDGE CB21 6GH UNITED KINGDOM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bee, Jared Gaithersburg, US 8 12
Dimitrova, Mariana Medford, US 8 39
Du, Jiali Gaithersburg, US 4 17
Santacroce, Paul Gaithersburg, US 1 7

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