METHOD FOR PURIFICATION OF RECOMBINANT FACTOR XA DERIVATIVES

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United States of America Patent

APP PUB NO 20150239929A1
SERIAL NO

14406645

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Abstract

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Disclosed herein are methods and kits for purifying a serine protease. The methods entail loading the serine protease to a soybean trypsin inhibitor (STI) based affinity chromatograph, and eluting the serine protease with an elution buffer comprising an agent that disrupts interaction between the STI and the serine protease.

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Patent Owner(s)

Patent OwnerAddress
ALEXION PHARMACEUTICALS INC121 SEAPORT BOULEVARD BOSTON MA 02210

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lu, Genmin Burlingame, US 43 330
Sinha, Uma San Francisco, US 72 710

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