Crystalline polymorphic form of ulipristal acetate
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United States of America Patent
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May 9, 2017
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Aug 27, 2015
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Sep 26, 2013
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Sep 28, 2012
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Abstract
A novel crystalline polymorphic form of ulipristal acetate useful as an agent for preventing and/or treating uterine leiomyoma and as a contraceptive, and a process for producing the crystalline polymorphic form are provided. The novel crystalline polymorphic form of ulipristal acetate is obtained by dissolving an isopropanol-solvated crystal of ulipristal acetate in a mixed solvent containing ethanol and water, and crystallizing an ulipristal acetate from the solution without addition of a seed crystal to the solution.
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