INHIBITORS OF BETA-SECRETASE

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20150239849A1
SERIAL NO

14662553

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the β-secretase enzyme (BACE1) activity, pharmaceutical compositions containing the same, and methods of using the same as therapeutic agents in the treatment of neurodegenerative disorders, disorders characterized by cognitive decline, cognitive impairment, dementia and diseases characterized by production of β-amyloid aggregates.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
VITAE PHARMACEUTICALS INC502 WEST OFFICE CENTER DRIVE FORT WASHINGTON PA 19034

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bukhtiyarov, Yuri Boothwyn, US 9 37
Cacatian, Salvacion Conshohocken, US 49 482
Dillard, Lawrence Wayne Yardley, US 31 225
Dorner-Ciossek, Cornelia Ingelheim Am Rhein, DE 41 281
Fuchs, Klaus Ingelheim Am Rhein, DE 42 389
Gross, Ulrike Ingelheim Am Rhein, DE 4 8
Heine, Niklas Ingelheim Am Rhein, DE 54 282
Jia, Lanqi Horsham, US 42 281
Lala, Deepak S Lower Gwynedd, US 8 55
Morales-Ramos, Angel Blue Bell, US 15 101
Sauer, Achim Ingelheim Am Rhein, DE 22 474
Singh, Suresh B Kendall Park, US 95 1396
Venkatraman, Shankar Lansdale, US 106 957
Xu, Zhenrong Chalfont, US 57 628
Yuan, Jing Lansdale, US 135 622
Zhao, Yi Blue Bell, US 234 2740
Zheng, Yajun Hockessin, US 73 365

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation