CRYSTALLINE FORMS OF AFATINIB DI-MALEATE
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United States of America Patent
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Issued Date -
Aug 20, 2015
app pub date -
Apr 25, 2012
filing date -
Oct 6, 2011
priority date (Note) -
Abandoned
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Abstract
Crystalline forms of Afatinib di-maleate are described in the present application and processes for their preparation. The present invention also includes pharmaceutical compositions of such crystalline forms of Afatinib di-maleate, methods of their preparation and the use thereof hi the treatment of a patient in need thereof. The present invention also describes preparing Afatinib free base and salts of Afatinib, other than Afatibin di-maleate, and solid forms thereof.
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