DUAL PHASE COLUMN MEMBRANE PROTEIN MICRO-REACTOR AND USE THEREOF
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United States of America Patent
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Aug 20, 2015
app pub date -
Jun 7, 2013
filing date -
Sep 20, 2012
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Abstract
The present invention relates to a biphasic microreactor for membrane proteins pretreatment comprising cation exchange and anion exchange materials packed in sequence in a container as stationary phase, where membrane proteins capture, pH adjustment, reduction, alkylation and tryptic digestion processed in situ. Thus the microreactor has advantages of high recovery, ease of operation, high efficiency and high throughput.
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