Molecular assay reagents and methods

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United States of America Patent

PATENT NO 9863004
SERIAL NO

14356368

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Abstract

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Methods, kits, and compositions for evaluating the quality of nucleic acids within a biological sample for analysis in a molecular assay are provided. A kit is provided for evaluating a biological sample containing potentially degraded DNA, comprising a control reagent and a target amplification reagent, wherein the control amplification reagent comprises one or more pairs of amplification oligonucleotides capable of amplifying a medium chain acyl-coenzyme A dehydrogenase (MCAD) nucleic acid molecule or a complement thereof, and wherein the target amplification reagent comprises one or more pairs of amplification oligonucleotides capable of amplifying a non-MCAD target gene of interest or a complement thereof. Frequently, one or more of the amplification oligonucleotides is/are labeled.

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Patent Owner(s)

Patent OwnerAddress
GEN-PROBE INCORPORATED10210 GENETIC CENTER DRIVE SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Higgins, Scott Portishead, GB 23 517
Webb, Mike Holcot, GB 18 442

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges233313951733621842312101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0200400600800100012001400160018002000220024002600

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