METHOD OF PREDICTING A PREDISPOSITION TO QT PROLONGATION
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United States of America Patent
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Apr 23, 2015
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Apr 6, 2009
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Abstract
The present invention describes an association between genetic polymorphisms in the FAM13A1 (family with sequence similarity 13, member A1) gene and a predisposition to prolongation of the QT interval, and provides related methods for the prediction of such a predisposition, the administration of QT interval-prolonging compounds to individuals having such a predisposition, and determining whether a compound is capable of inducing QT prolongation.
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