BIOMARKER FOR VASCULAR ENDOTHELIAL FUNCTION
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United States of America Patent
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Aug 13, 2015
app pub date -
Jul 31, 2013
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Aug 1, 2012
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Abstract
A method of determining the vascular endothelial function of a subject using GAPDH as a biomarker is presented, whereby the level of GAP-DH mRNA and/or GAPDH protein in a sample obtained from a subject is measured and compared to a reference. A difference in the level of GAPDH mRNA and/or GAPDH protein between that measured for the sample and a reference may be indicative of impaired vascular endothelial function and therefore may indicate the onset of a condition related to impaired vascular endothelial function such as atherosclerosis.
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