TETRABRANCHED PEPTIDES AND ANALOGUES AS A NEW CLASS OF ANTIMICROBIALS AND THEIR PREPARATION THEREOF

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United States of America Patent

APP PUB NO 20150225454A1
SERIAL NO

14426822

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Abstract

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An isolated peptide tetramer includes the formula [(RGRKVVRR)2K]2KK and its derivatives thereof. The derivatives may include at least one amino acid substitution, at least one amino acid deletion, a rearrangement of the peptide monomer and/or at least one non-proteogenic amino acid modification in at least one peptide monomer. The isolated peptide tetramer and derivatives thereof have antimicrobial (antibacterial, antifungal and/or anti-protozoan) properties.

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Patent Owner(s)

Patent OwnerAddress
AGENCY FOR SCIENCE TECHNOLOGY AND RESEARCH2 FUSIONOPOLIS WAY #08-01 INNOVIS SINGAPORE 13863
SINGAPORE HEALTH SERVICES PTE LTD31 THIRD HOSPITAL AVENUE #03-03 BOWYER BLOCK C SINGAPORE 168753

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beuerman, Roger Singapore, SG 11 66
Li, Jianguo Singapore, SG 169 2228
Liu, Shouping Singapore, SG 10 19
Rajamani, Lakshminarayanan Sinagpore, SG 8 4
Verma, Chandra Singapore, SG 4 1

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