NEAR-INFRARED SPECTROSCOPY AND OPTICAL REPORTER
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United States of America Patent
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Aug 6, 2015
app pub date -
Aug 9, 2013
filing date -
Aug 10, 2012
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Abstract
The method of the present disclosure is directed towards a method for determining the concentration of an analyte in a mammal's bloodstream. This method includes the following steps; applying a patch to the mammal's skin, the patch configured to transmit a reporter through the mammal's skin, wherein the reporter is configured to have an affinity for the analyte and is capable of exhibiting a detectable change in fluorescence upon binding to the analyte, subjecting a portion of the mammal's skin to Near Infrared Spectroscopy (NIRS), detecting fluorescence emission intensity and calculating the concentration of the analyte based on the detected fluorescence emission. The system of the present disclosure is directed towards an analyte monitoring system. The system includes the following, a patch and a receiver
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