METHODS AND COMPOSITIONS FOR IDENTIFYING, CLASSIFYING AND MONITORING SUBJECT HAVING BCL-2 FAMILY INHIBITOR-RESISTANT TUMORS AND CANCERS

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United States of America Patent

APP PUB NO 20150211075A1
SERIAL NO

14679889

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention is directed to methods and kits that allow for identifying, classifying, and monitoring cancer patients for Bcl-2 family inhibitor therapies. The methods and compositions of the invention are directed to determining amplification of Bcl-xL and in cancer or tumor cells, or elevated Bcl-xL polypeptide expression.

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Patent Owner(s)

Patent OwnerAddress
ABBVIE INC1 NORTH WAUKEGAN ROAD NORTH CHICAGO IL 60064
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH1G ROYAL PARADE PARKVILLE MELBOURNE 3052

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Huang, David Ching Siang Fitzroy North, AU 13 79
Lesniewski, Richard R Collegeville, US 10 67
Semizarov, Dimitri Chicago, US 20 63
Tse, Christin Libertyville, US 16 85
Uziel, Tamar Deerfield, US 3 0
van, Delft Mark F Toronto, CA 2 0

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