GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

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United States of America Patent

SERIAL NO

14427275

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, cystic disease and for the treatment of cancer.

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Patent Owner(s)

Patent OwnerAddress
GENZYME CORPORATION450 WATER STREET CAMBRIDGE MA 02141

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beskrovnaya, Oxana Southborough, US 12 60
Bourque, Elyse Blaine, US 21 120
Cabrera-Salazar, Mario A Brighton, US 4 29
Celatka, Cassandra Chesterfield, US 25 135
Cheng, Seng H Wellesley, US 102 1860
Good, Andrew Wallingford, US 36 298
Hirth, Bradford Littleton, US 14 88
Husson, Herve Boston, US 5 44
Jancsics, Katherine Wilmington, US 9 53
Leonard, John Bridgewater, US 58 653
Makino, Elina Winchester, US 14 56
Marshall, John Hopedale, US 331 5430
Metz, Markus Waltham, US 55 269
Natoli, Thomas Southborough, US 5 38
Scheule, Ronald K Hopkinton, US 31 684
Skerlj, Renato Newton, US 47 518
Xiang, Yibin Dracut, US 39 565
Zhao, Zhong Wayland, US 40 480

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