PLASMA ANALYTES PREDICT DIAGNOSIS AND PROGNOSIS OF THORACIC AORTIC ANEURYSM

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United States of America Patent

APP PUB NO 20150203916A1
SERIAL NO

14411126

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ATTORNEY / AGENT: (SPONSORED)

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Disclosed are methods and materials for assessing thoracic aortic aneurysm using a combination of protein and microRNA biomarkers. The presence or levels of the biomarkers can be measured in a body fluid, such as plasma and serum, or in cardiac tissue, to predict the presence and severity of TAA in a subject. This can be used to diagnose and monitor TAA, providing early detection of a lethal and silent disease, as well as reduce the frequency of radiological procedures, which are costly and potentially dangerous.

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Patent Owner(s)

Patent OwnerAddress
MEDICAL UNIVERSITY OF SOUTH CAROLINA171 ASHLEY AVENUE CHARLESTON SC 29425
DEPARTMENT OF VETERANS AFFAIRSOFFICE OF THE GENERAL COUNSEL WASHINGTON DC 20420

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ikonomidis, John S Mount Pleasant, US 3 25
Jones, Jeffrey A Charleston, US 55 919
Rupak, Mukherjee Charleston, US 1 3
Stroud, Robert E Mount Pleasant, US 6 48
Zile, Michael R Charleston, US 6 28

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