Topographically Functionalized NFC Film as an Immunoassay Platform for Rapid Diagnostics
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United States of America Patent
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Jul 23, 2015
app pub date -
Jun 28, 2013
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Jun 28, 2012
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Abstract
The present invention concerns a method for functionalization, via topographical modification, of the surfaces of nanofibrillated (NFC) cellulose films into non-porous, water-resistant platforms, usable in diagnostic applications. The method includes a carboxylation of the NFC-film via TEMPO-mediated oxidation, and optionally an activation via EDS/NHS chemistry and, finally, the reactivity of the film can be tested using anti-human IgG. The invention also concerns the thus prepared functionalized NFC films, as well as the use thereof as platforms for diagnostical assays.
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