STRUCTURE OF INSULIN IN COMPLEX WITH N- AND C-TERMINAL REGIONS OF THE INSULIN RECEPTOR ALPHA-CHAIN

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United States of America Patent

APP PUB NO 20150198619A1
SERIAL NO

14430220

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Abstract

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The present invention relates to the crystal structure of the insulin receptor ectodomain in complex with human insulin and to methods of using the crystal and related structural information to identify, design and screen for compounds that interact with or modulate the insulin receptor and insulin receptor signalling.

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Patent Owner(s)

Patent OwnerAddress
WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCHPARKVILLE VIC 3050

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lawrence, Michael Colin Parkville, AU 5 21
Menting, John Gerbrandt Tasman Parkville, AU 4 2
Smith, Brian John Parkville, AU 10 262

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