OXYGEN-RESPONSIVE BACTERIAL GENE SWITCH

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United States of America Patent

SERIAL NO

14597466

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Abstract

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The invention provided herein relates to sequence determinants that elicit certain levels of gene expression and methods for obtaining engineered ligand-responsive gene switches comprising these sequence determinants. More particularly, the invention provided herein relates to molecular building blocks (i.e., discrete nucleotide sequences), synthetic ligand-responsive gene switches comprising an assembly of these molecular building blocks, and methods of using synthetic ligand-responsive gene switches as customizable and controllable expression systems and sensors.

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WISCONSIN ALUMNI RESEARCH FOUNDATION614 WALNUT STREET 13TH FLOOR MADISON WI 53726

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  • 2015 Application Filing Year
  • C12N Class
  • 6649 Applications Filed
  • 4472 Patents Issued To-Date
  • 67.26 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kiley, Patricia J Middleton, US 2 1
Park, Dan M Dublin, US 2 1

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges24532564290903213641301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7091 - 100100 +02004006008001000120014001600180020002200240026002800

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