SYSTEM AND METHOD FOR USING ULTRASOUND-STIMULATED MICROBUBBLE EXPOSURES TO INDUCE CERAMIDE ACCUMULATION IN ENDOTHELIAL AND TUMOR CELLS
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United States of America Patent
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N/A
Issued Date -
Jul 16, 2015
app pub date -
Jul 8, 2013
filing date -
Jul 8, 2012
priority date (Note) -
Published
status (Latency Note)
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Abstract
A system and method for using ultrasound and a microbubble agent to induce ceramide accumulation in a target region including a population of cells associated with a tumor. An ultrasound system is directed to expose a target region in a patient, to which a microbubble agent has been provided, to an ultrasound exposure sufficient to alter gene expressions in cells in the target region so as to induce an accumulation of ceramide in the cells.
First Claim
all claims..Other Claims data not available
Family
Country | kind | publication No. | Filing Date | Type | Sub-Type |
---|---|---|---|---|---|
WO | A1 | WO2014008594 | Jul 08, 2013 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
INTERNATIONAL APPLICATION PUBLISHED WITH INTERNATIONAL SEARCH REPORT | SYSTEM AND METHOD FOR USING ULTRASOUND-STIMULATED MICROBUBBLE EXPOSURES TO INDUCE CERAMIDE ACCUMULATION IN ENDOTHELIAL AND TUMOR CELLS | Jan 16, 2014 | |||
EP | A1 | EP2869815 | Jul 08, 2013 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
APPLICATION PUBLISHED WITH SEARCH REPORT | SYSTEM AND METHOD FOR USING ULTRASOUND-STIMULATED MICROBUBBLE EXPOSURES TO INDUCE CERAMIDE ACCUMULATION IN ENDOTHELIAL AND TUMOR CELLS | May 13, 2015 | |||
CA | A1 | CA2878491 | Jul 08, 2013 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
APPLICATION LAID OPEN | SYSTEM AND METHOD FOR USING ULTRASOUND-STIMULATED MICROBUBBLE EXPOSURES TO INDUCE CERAMIDE ACCUMULATION IN ENDOTHELIAL AND TUMOR CELLS | Jan 16, 2014 |
- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
SUNNYBROOK HEALTH SCIENCES CENTRE | TORONTO ON M4N 3M5 |
International Classification(s)

- 2013 Application Filing Year
- A61K Class
- 12711 Applications Filed
- 11051 Patents Issued To-Date
- 86.95 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Almahrouki, Azza | Scarborough, CA | 1 | 6 |
# of filed Patents : 1 Total Citations : 6 | |||
Burns, Peter Nicholas | Toronto, CA | 1 | 6 |
# of filed Patents : 1 Total Citations : 6 | |||
Czarnota, Gregory J | Oakville, CA | 7 | 49 |
# of filed Patents : 7 Total Citations : 49 | |||
Giles, Anoja | North York, CA | 1 | 6 |
# of filed Patents : 1 Total Citations : 6 | |||
Karshafian, Raffi | Richmond Hill, CA | 4 | 14 |
# of filed Patents : 4 Total Citations : 14 | |||
Kim, Christina | Toronto, CA | 5 | 79 |
# of filed Patents : 5 Total Citations : 79 | |||
Tran, William Tyler | Toronto, CA | 2 | 8 |
# of filed Patents : 2 Total Citations : 8 | |||
Wong, Emily | Toronto, CA | 3 | 13 |
# of filed Patents : 3 Total Citations : 13 |
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Patent Citation Ranking
- 6 Citation Count
- A61K Class
- 31.06 % this patent is cited more than
- 10 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
---|---|---|---|---|
11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jan 16, 2027 |
Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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