SYSTEM AND METHOD FOR USING ULTRASOUND-STIMULATED MICROBUBBLE EXPOSURES TO INDUCE CERAMIDE ACCUMULATION IN ENDOTHELIAL AND TUMOR CELLS

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United States of America Patent

APP PUB NO 20150196638A1
SERIAL NO

14413623

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Abstract

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A system and method for using ultrasound and a microbubble agent to induce ceramide accumulation in a target region including a population of cells associated with a tumor. An ultrasound system is directed to expose a target region in a patient, to which a microbubble agent has been provided, to an ultrasound exposure sufficient to alter gene expressions in cells in the target region so as to induce an accumulation of ceramide in the cells.

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Patent Owner(s)

Patent OwnerAddress
SUNNYBROOK HEALTH SCIENCES CENTRETORONTO ON M4N 3M5

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Almahrouki, Azza Scarborough, CA 1 6
Burns, Peter Nicholas Toronto, CA 1 6
Czarnota, Gregory J Oakville, CA 7 49
Giles, Anoja North York, CA 1 6
Karshafian, Raffi Richmond Hill, CA 4 14
Kim, Christina Toronto, CA 5 79
Tran, William Tyler Toronto, CA 2 8
Wong, Emily Toronto, CA 3 13

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