TYPE 1 INTERFERON DIAGNOSTIC

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United States of America Patent

APP PUB NO 20150191788A1
SERIAL NO

14662134

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Abstract

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The present disclosure encompasses type-I IFN and IFNα-induced PD marker expression profiles, kits, and methods for identifying such IFNα-induced PD marker expression profiles. The type-I IFN and IFNα-induced PD marker expression profiles may also be used in, for example, methods of treating patients having a type-I IFN or IFNα-mediated disorder, methods of monitoring disease progression of patients receiving treatment with a therapeutic agent that modulates type 1 interferon activity, identifying patients as candidates to receive a therapeutic that binds to and neutralizes IFNα activity, and in diagnosing or providing a prognosis to patients having IFNα-induced disorders.

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Patent Owner(s)

Patent OwnerAddress
MEDIMMUNE LLCONE MEDIMMUNE WAY GAITHERSBURG MD 20878

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HIGGS, BRANDON GAITHERSBURG, US 35 168
JALLAL, BAHIJA POTOMAC, US 33 267
MOREHOUSE, CHRIS MIDDLETOWN, US 8 6
WHITE, BARBARA FINKSBURG, US 9 55
YAO, YIHONG BOYDS, US 52 114
ZHU, WEI GAITHERSBURG, US 383 5693

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