ANTIBODIES THAT RECOGNIZE IAPP

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United States of America Patent

APP PUB NO 20150191541A1
SERIAL NO

14561609

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides monoclonal antibody 8A9 and related antibodies. The 8A9 antibody binds to an epitope within residues 1-10 of IAPP. The antibodies of the invention are useful, for example, for treating disorders associated with IAPP accumulation, particularly accumulation of IAPP deposits. Such disorders include type 2 diabetes, metabolic syndrome, impaired insulin tolerance, impaired glucose tolerance, insulinomas, and related conditions.

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Patent Owner(s)

Patent OwnerAddress
PROTHENA BIOSCIENCES LIMITEDADELPHI PLAZA UPPER GEORGE STREET DÚN LAOGHAIRE CO DUBLIN A96 T927 IRELAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barbour, Robin Walnut Creek, US 73 603
Nijjar, Tarlochan S Orinda, US 69 533

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