METHODS OF TREATING ALZHEIMER'S DISEASE WITH APO A-1 MILANO

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United States of America Patent

APP PUB NO 20150191527A1
SERIAL NO

14536445

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Abstract

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This invention relates to the treatment of Alzheimer's disease, the reduction of the progression of Alzheimer's disease, and the alleviation of symptoms of Alzheimer's disease by administering ApoA-1 Milano based therapies to provide anti-inflammatory, antioxidant, and lipid depleting effects to brain tissue. In particular embodiments, the method comprises administering a composition comprising an rAAV vector encoding ApoA-1 Milano or an active fragment thereof, to a mammal having Alzheimer's disease or a symptom of Alzheimer's disease.

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Patent Owner(s)

Patent OwnerAddress
CEDARS-SINAI MEDICAL CENTER8700 BEVERLY BOULEVARD LOS ANGELES CALIFORNIA 90048 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Shah, Prediman K Los Angeles, US 44 236

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